Riley Leonard is set to get his first start at quarterback with the hopes to, not only establish himself as Indy's QB2 going forward, but pull off a massive victory to help the Colts finish with a winning record, albeit 9-8.

The Colts' playoff chances dropped to 10% after a recent loss to the Seahawks. If the Colts win their last three games, their playoff odds increase to 97%. Losing to either the Jaguars or Texans would drop the Colts' playoff chances to between 12-15%.

But even with their backups running the show, the Texans’ second-string defense held down the fort, stunting a confident first start by Indianapolis’ Riley Leonard, and setting up the offense to go ahead on a 43-yard Kaʻimi Fairbairn field goal with 12 seconds to play.

Ahead of the team's game vs the Jaguars, the Colts made a series of roster and injury updates including placing three players on season-ending IR.

In a disappointing Week 17 contest, the Indianapolis Colts fell to the Jacksonville Jaguars 23–17, a loss that adds insult to injury after already being eliminated from playoff contention. It was the team's sixth consecutive loss. Here's everything to know from the Colts ' performance.

Brenton Strange has been a trusted red-zone target for Trevor Lawrence, and our Jaguars vs. Colts predictions expect the QB to find him in the end zone this weekend.

Sauce Gardner is ruled out for the Indianapolis Colts' Week 18 matchup due to a calf injury, effectively ending his season.

Indianapolis Colts' head coach Shane Steichen is "hopeful" that cornerback Sauce Gardner could return this week against the Jacksonville Jaguars. Steichen said that Gardner is progressing well with his calf injury. "Hopeful that he can go," Steichen told reporters.

The Texans are healthy for the most part, but injuries throughout the games could warrant a weekend of rest. In Saturday's 20-16 win over the Chargers, both cornerbacks Kamari Lassiter (foot) and Derek Stingley Jr. (oblique), left before entually returning to close out the game.

In a hard-fought Week 17 AFC South showdown in Indianapolis, the Jacksonville Jaguars climbed out of an early hole to defeat the Colts 23–17, showcasing resilience on both sides of the ball and tightening their grip on the division race.

Pittsburgh Steelers wide receiver Calvin Austin III has been cleared to play against the Baltimore Ravens after a one-game absence.